Psychostimulant prescribing trends in a paediatric population in Ireland: a national cohort study

TitlePsychostimulant prescribing trends in a paediatric population in Ireland: a national cohort study
Publication TypePublished Journal Article
2015
AuthorsBoland F, Galvin R, Reulbach U, Motterlini N, Kelly D, Bennett K, Fahey T
JournalBMC Pediatrics
Volume15
Issue118
Date Published09/2015
KeywordsADHD, children, pharmacoepidemiology, Psychostimulant treatment
Abstract

Background: Psychotropic paediatric prescribing trends are increasing internationally. The aim of this study is to examine
the prevalence and secular trends in psychotropic prescribing in Irish children and adolescents between 2002 and 2011.
Methods: Data was obtained from the Irish General Medical Services (GMS) scheme pharmacy claims database
from the Health Service Executive Primary Care Reimbursement Services (HSE-PCRS). Prescribing rates per 1000
eligible population and associated 95 % confidence intervals (CIs) were calculated across years (2002–2011), age
groups (0–4, 5–11, 12–15 years) and gender. Rates of concomitant prescriptions for psycholeptics and
antidepressants were also examined. The total expenditure costs were calculated and expressed as a percentage of
the cost of all prescriptions for this age group (≤15 years).
Results: In 2002, 3.77/1000 GMS population (95 % CI: 3.53–4.01) received at least one psychostimulant prescription and this
rate increased to 8.63/1000 GMS population (95 % CI: 8.34–8.92) in 2011. Methylphenidate was the most frequently prescribed
psychostimulant. For both males and females the prevalence of medication use was highest among the 12–15 year old
group. On average, a psycholeptic medication was prescribed to 8 % of all psychostimulant users and an antidepressant was
concomitantly prescribed on average to 2 %. Total expenditure rose from €89,254 in 2002 to €1,532,016 in 2011.
Conclusions: The rate and cost of psychostimulant prescribing among GMS children and adolescents in Ireland increased
significantly between 2002 and 2011. Further research is necessary to assess the safety, efficacy and economic impact of
concomitant psychotropic prescribing in this population.

URLhttp://www.biomedcentral.com/1471-2431/15/118
DOI10.1186/s12887-015-0435-3